*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : NS6220000 CHEMICAL NAME : Isonipecotic acid, 4-phenyl-1-(2-((tetrahydrofurfuryl)oxy)ethyl)-, ethyl ester, hydrochloride LAST UPDATED : 199512 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C21-H31-N-O4.Cl-H MOLECULAR WEIGHT : 397.99 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * Furethidine hydrochloride * 4-Phenyl-1-(2-((tetrahydrofurfuryl)oxy)ethyl)isonipecotic acid ethyl ester hydrochloride * TA 48 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 25 mg/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - respiratory depression REFERENCE : BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 15,247,1960 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 30 mg/kg/12D-I TOXIC EFFECTS : Lungs, Thorax, or Respiration - respiratory depression Related to Chronic Data - death REFERENCE : BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 15,247,1960 *** END OF RECORD ***