*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : NT2544000
CHEMICAL NAME : Isophthalic acid, 4-hydroxy-
CAS REGISTRY NUMBER : 636-46-4
BEILSTEIN REFERENCE NO. : 2211981
REFERENCE : 4-10-00-02091 (Beilstein Handbook Reference)
LAST UPDATED : 199612
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C8-H6-O5
MOLECULAR WEIGHT : 182.14
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* 1,3-Benzenedicarboxylic acid, 4-hydroxy-
* Eupirina
* 4-HIPA
* 4-Hydroxy-1,3-benzenedicarboxylic acid
* 4-Hydroxyisophthalic acid
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1071 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK)
V.1-33, 1946-68. For publisher information, see BJPCBM.
Volume(issue)/page/year: 11,20,1956
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
Italy) V.8-43 1953-88 For publisher information, see FRMCE8
Volume(issue)/page/year: 16,200,1961
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 73500 mg/kg/14W-C
TOXIC EFFECTS :
Related to Chronic Data - death
REFERENCE :
BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK)
V.1-33, 1946-68. For publisher information, see BJPCBM.
Volume(issue)/page/year: 11,20,1956
*** END OF RECORD ***