*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NW6510000
CHEMICAL NAME           : Isoquinaldaldehyde, thiosemicarbazone
CAS REGISTRY NUMBER     : 2365-26-6
LAST UPDATED            : 199212
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C11-H10-N4-S
MOLECULAR WEIGHT        : 230.31
WISWESSER LINE NOTATION : T66 CNJ B1UNMYZUS
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * 1-Formylisoquinoline thiosemicarbazone
   * Hydrazinecarbothioamide, 2-(1-isoquinolinymethylene)-
   * IQ 1
   * Isoquinaldehyde thiosemicarbazone
   * 2-(1-Isoquinolinylmethylene)hydrazinecarbothioamide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 9,585,1966
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 2500 umol/L
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   21,3213,1972
 
TYPE OF TEST            : DNA damage
TEST SYSTEM             : Rodent - mouse Ascites tumor
DOSE/DURATION           : 30 mg/kg
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   24,1631,1975
 
                            *** END OF RECORD ***