*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NW6750000
CHEMICAL NAME           : Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one,
                          5,9,10,14b-tetrahydro-5,10-dimethyl-, cis-
LAST UPDATED            : 199103
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C19-H20-N2-O
MOLECULAR WEIGHT        : 292.41
WISWESSER LINE NOTATION : T C6 B676 KN MVN&TT&J I1 N1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   cis-5,9,10,14b-Tetrahydro-5,10-dimethylisoquino(2,1-d)(1,4)benzodiazepin
     -6(7H)-one
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 275 mg/kg
TOXIC EFFECTS :
   Behavioral - anticonvulsant
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 11,777,1968
 
                            *** END OF RECORD ***