*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NR3440500
CHEMICAL NAME           : 2-Isoindolineacetic acid, 1,3-dioxo-, vinyl ester
CAS REGISTRY NUMBER     : 2756-76-5
BEILSTEIN REFERENCE NO. : 0211739
REFERENCE               : 5-21-10-00432 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C12-H9-N-O4
MOLECULAR WEIGHT        : 231.22
WISWESSER LINE NOTATION : T56 BVNVJ C1VO1U1
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * 1,3-Dioxo-2-isoindolineacetic acid vinyl ester
   * N-Phthaloylglycine vinyl ester
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 280 mg/kg
SEX/DURATION            : female 28 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - female fertility index (e.g. # females pregnant
   per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 70,60,1981
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravaginal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 280 mg/kg
SEX/DURATION            : female 28 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - female fertility index (e.g. # females pregnant
   per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 70,60,1981
 
                            *** END OF RECORD ***