*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NW7524000
CHEMICAL NAME           : Isoquinoline, 1-(3,4-diethoxybenzyl)-6,7-diethoxy-
CAS REGISTRY NUMBER     : 486-47-5
BEILSTEIN REFERENCE NO. : 0342349
REFERENCE               : 5-21-06-00183 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C24-H29-N-O4
MOLECULAR WEIGHT        : 395.54
WISWESSER LINE NOTATION : T66 CNJ B1R CO2 DO2& HO2 IO2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Barbonin
   * Barbonine
   * 6,7-Diaethoxy-1-(3,4-diaethoxybenzyl)isochinolin
   * 1-(3,4-Diethoxybenzyl)-6,7-diethoxyisoquinoline
   * 6,7-Diethoxy-1-(3,4-diethoxybenzyl)isoquinoline
   * Dyscural
   * Ethaverine
   * Ethylpapaverine
   * Isoquinoline, 6,7-diethoxy-1-(3,4-diethoxybenzyl)-
   * Isoquinoline, 1-((3,4-diethoxyphenyl)methyl)-6,7-diethoxy-
   * Perparine
   * Perperine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 45600 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 28,794,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PDHU** "Ueber die Wirksamkeit einiger aliphatischaromatischer Amine, einiger
   Isochinolin derivate, sowie eines Chinolinabkommlings und einer
   Barbitursaure auf die Erreger der Schlafkrankheit bei Tieren, Dissertation,"
   Puls, A., University of Hamburg, Fed. Rep. Ger., 1936
   Volume(issue)/page/year: -,-,1936
 
                            *** END OF RECORD ***