*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : NR3459000 CHEMICAL NAME : 2-Isoindolinebutyric acid, 1,3-dioxo- CAS REGISTRY NUMBER : 3130-75-4 BEILSTEIN REFERENCE NO. : 0208243 REFERENCE : 5-21-10-00481 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C12-H11-N-O4 MOLECULAR WEIGHT : 233.24 WISWESSER LINE NOTATION : T56 BVNVJ C3VQ COMPOUND DESCRIPTOR : Drug Reproductive Effector SYNONYMS/TRADE NAMES : * 1,3-Dihydro-1,3-dioxo-2H-isoindole-2-butanoic acid * 2H-Isoindole-2-butanoic acid, 1,3-dihydro-1,3-dioxo- * 4-Phthalimidobuttersaure * 4-Phthalimidobutyric acid * N-Phthaloyl GABA *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 327 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold REFERENCE : IJEBA6 Indian Journal of Experimental Biology. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- Volume(issue)/page/year: 27,805,1989 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE : 400 mg/kg SEX/DURATION : female 9 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - other developmental abnormalities REFERENCE : PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 28,680,1973 *** END OF RECORD ***