*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NR3459000
CHEMICAL NAME           : 2-Isoindolinebutyric acid, 1,3-dioxo-
CAS REGISTRY NUMBER     : 3130-75-4
BEILSTEIN REFERENCE NO. : 0208243
REFERENCE               : 5-21-10-00481 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C12-H11-N-O4
MOLECULAR WEIGHT        : 233.24
WISWESSER LINE NOTATION : T56 BVNVJ C3VQ
COMPOUND DESCRIPTOR     : Drug
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * 1,3-Dihydro-1,3-dioxo-2H-isoindole-2-butanoic acid
   * 2H-Isoindole-2-butanoic acid, 1,3-dihydro-1,3-dioxo-
   * 4-Phthalimidobuttersaure
   * 4-Phthalimidobutyric acid
   * N-Phthaloyl GABA
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 327 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   IJEBA6 Indian Journal of Experimental Biology.  (Publications & Information
   Directorate, CSIR, Hillside Rd., New Delhi 110 012, India)  V.1-    1963-
   Volume(issue)/page/year: 27,805,1989
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 400 mg/kg
SEX/DURATION            : female 9 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Specific Developmental Abnormalities - other developmental
   abnormalities
REFERENCE :
   PHARAT Pharmazie.  (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18,
   Berlin DDR-1020, Ger. Dem. Rep.)  V.1-    1946-  Volume(issue)/page/year:
   28,680,1973
 
                            *** END OF RECORD ***