*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NW7628500
CHEMICAL NAME           : Isoquinoline,
                          3,4-dihydro-6,7-dimethoxy-1-(3,4-dimethoxyphenethyl)-
                          , hydrochloride
CAS REGISTRY NUMBER     : 81182-04-9
LAST UPDATED            : 198609
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H25-N-O4.Cl-H
MOLECULAR WEIGHT        : 391.93
WISWESSER LINE NOTATION : T66 CN BUT&J B2R CO1 DO1& HO1 IO1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 3,4-Dihydro-6,7-dimethoxy-1-(3,4-dimethoxyphenethyl)isoquinoline  
   hydrochloride
   * Homodihydropapaverine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 900 mg/kg
TOXIC EFFECTS :
   Vascular - BP lowering not characterized in autonomic section
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 149,200,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Vascular - BP lowering not characterized in autonomic section
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 149,200,1964
 
                            *** END OF RECORD ***