*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : NW7628980 CHEMICAL NAME : Isoquinoline, 3,4-dihydro-6,7-dimethoxy-1-veratryl-, hydrochloride CAS REGISTRY NUMBER : 5884-22-0 LAST UPDATED : 198609 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C20-H23-N-O4.Cl-H MOLECULAR WEIGHT : 377.90 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * Chlorhydrate de dihydropapaverine * 3,4-Dihydro-6,7-dimethoxy-1-veratrylisoquinoline hydrochloride * Dihydropapaverine hydrochloride * 3,4-Dihydropapaverine hydrochloride * 1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-3,4-dihydroisoquinoline hydrochloride * 6,7-Dimethoxy-1-(3,4-dimethoxybenzyl)-3,4-dihydroisoquinoline hydrochloride * Isoquinoline, 3,4-dihydro-6,7-dimethoxy-1-((3,4-dimethoxyphenyl)methyl)-, hydrochloride *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 500 mg/kg TOXIC EFFECTS : Behavioral - tremor Behavioral - convulsions or effect on seizure threshold REFERENCE : APPBDI Acta Physiologica et Pharmacologica Bulgarica. (Izdatelstvo na Bulgarskata Akademiya na Naukite, ul. Akad. G. Bonchev, 1113 Sofia, Bulgaria) V.1- 1974- Volume(issue)/page/year: 5(3),82,1979 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 320 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 5,69,1950 *** END OF RECORD ***