*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NW7629000
CHEMICAL NAME           : Isoquinoline,
                          3,4-dihydro-1-(p-(isopropylsulfonyl)phenyl)-6,7-dimet
                          hoxy-
CAS REGISTRY NUMBER     : 18453-36-6
BEILSTEIN REFERENCE NO. : 1505735
REFERENCE               : 5-21-05-00646 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H23-N-O4-S
MOLECULAR WEIGHT        : 373.50
WISWESSER LINE NOTATION : T66 CN BUT&J BR DSWY1&1& HO1 IO1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 3,4-Dihydro-1-(p-(isopropylsulfonyl)phenyl)-6,7-dimethoxy-isoquinoline
   * 1-((p-Isopropylsulfonyl)phenyl)-6,7-dimethoxy-3,4-dihydro-isoquinoline
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 350 mg/kg
TOXIC EFFECTS :
   Behavioral - anticonvulsant
   Behavioral - muscle weakness
   Behavioral - antipsychotic
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 11,1023,1968
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 11,1023,1968
 
                            *** END OF RECORD ***