*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NW8220000
CHEMICAL NAME           : Isoquinoline, 6,7-dimethoxy-1-methyl-
CAS REGISTRY NUMBER     : 4594-02-9
BEILSTEIN REFERENCE NO. : 0148112
REFERENCE               : 5-21-05-00151 (Beilstein Handbook Reference)
LAST UPDATED            : 199712
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C12-H13-N-O2
MOLECULAR WEIGHT        : 203.26
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 6,7-Dimethoxy-1-methylisoquinoline
   * Isosalsolidine
   * Nigellimine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 195 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   YKKZAJ Yakugaku Zasshi.  Journal of Pharmacy.  (Nippon Yakugakkai, 2-12-15
   Shibuya, Shibuya-ku, Tokyo 150, Japan)  No.1-    1881-
   Volume(issue)/page/year: 88,1197,1968
 
                            *** END OF RECORD ***