*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NX1423500
CHEMICAL NAME           : 1-Isoquinolinemethanol,
                          1,2,3,4-tetrahydro-2,3-dimethyl-6-methoxy-alpha-(m-me
                          thoxyphenyl)-, hydrochloride
CAS REGISTRY NUMBER     : 17606-15-4
LAST UPDATED            : 199007
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C20-H25-N-O3.Cl-H
MOLECULAR WEIGHT        : 363.92
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   1,2,3,4-Tetrahydro-2,3-dimethyl-6-methoxy-alpha-(m-methoxyphenyl)-1-isoq
     uinolinemethanol HCl
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Lungs, Thorax, or Respiration - dyspnea
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 11,752,1968
 
                            *** END OF RECORD ***