*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NX4919100
CHEMICAL NAME           : Isoquinoline,
                          1,2,3,4-tetrahydro-2-((1-butyl-4-phenyl-4-piperidinyl
                          )carbonyl)-
                          6,7-dimethoxy-1-((3,4-dimethoxyphenyl)methyl)-
CAS REGISTRY NUMBER     : 77172-81-7
LAST UPDATED            : 198510
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C36-H46-N2-O5
MOLECULAR WEIGHT        : 586.84
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * BG-9
   * N-(1-Butyl-4-phenyl-4-piperidinyl)tetrahydropapaverine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 107 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - analgesia
REFERENCE :
   PJPPAA Polish Journal of Pharmacology and Pharmacy.  (ARS Polona, POB 1001,
   00-068 Warsaw 1, Poland) V.25-    1973-  Volume(issue)/page/year:
   32,141,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - analgesia
REFERENCE :
   PJPPAA Polish Journal of Pharmacology and Pharmacy.  (ARS Polona, POB 1001,
   00-068 Warsaw 1, Poland) V.25-    1973-  Volume(issue)/page/year:
   32,141,1980
 
                            *** END OF RECORD ***