*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NX4952000
CHEMICAL NAME           : Isoquinoline,
                          1,2,3,4-tetrahydro-2-(p-chlorophenethyl)-6,7-dimethox
                          y-1-methyl-, fumarate
CAS REGISTRY NUMBER     : 1872-81-7
LAST UPDATED            : 199109
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H24-Cl-N-O2.C4-H4-O4
MOLECULAR WEIGHT        : 461.98
WISWESSER LINE NOTATION : T66 CNT&J B1 C2R DG& HO1 IO1 &QV1U1VQ -T
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   2-(p-Chlorophenethyl)-6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinol
     ine fumarate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 17,1145,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 55 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 17,1145,1967
 
                            *** END OF RECORD ***