*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NX5073200
CHEMICAL NAME           : Isoquinoline,
                          1,2,3,4-tetrahydro-2-(3-(ethylsulfinyl)propyl)-,
                          hydrochloride
CAS REGISTRY NUMBER     : 23486-22-8
LAST UPDATED            : 198205
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C14-H21-N-O-S.Cl-H
MOLECULAR WEIGHT        : 287.88
WISWESSER LINE NOTATION : T66 CNT&J C3SO&2 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Esproquin
   * 2-(3-Ethylsulfinylpropyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride
   * NC 7192
   * NC 7197
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 77 mg/kg
TOXIC EFFECTS :
   Cardiac - cardiac output
   Vascular - BP elevation not characterized in autonomic section
   Vascular - regional or general arteriolar or venous dilation
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 16,859,1973
 
                            *** END OF RECORD ***