*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NX5250000
CHEMICAL NAME           : Isoquinolinium, 2-dodecyl-, bromide
CAS REGISTRY NUMBER     : 93-23-2
LAST UPDATED            : 199701
DATA ITEMS CITED        : 12
MOLECULAR FORMULA       : C21-H32-N.Br
MOLECULAR WEIGHT        : 378.45
WISWESSER LINE NOTATION : T66 CKJ C12 &E
COMPOUND DESCRIPTOR     : Agricultural Chemical
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * Intexsan LQ75
   * Isothan
   * Isothan Q-15
   * Isothan Q-75
   * Isothan Q-90
   * Laurylisoquinolinium bromide
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2 mg
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 15,131,1977
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2 mg
REACTION SEVERITY       : Severe
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 15,131,1977
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 2 mg
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 15,131,1977
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Primate - monkey
DOSE/DURATION           : 2 mg
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 15,131,1977
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 2 mg
REACTION SEVERITY       : Moderate
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 15,131,1977
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 2 mg
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 15,131,1977
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - hamster
DOSE/DURATION           : 2 mg
REACTION SEVERITY       : Severe
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 15,131,1977
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 230 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - other changes
REFERENCE :
   SSCHAH Soap and Sanitary Chemicals.  (New York, NY)  V.14-30, 1938-54.  For
   publisher information, see SCCSC8.  Volume(issue)/page/year: 25,125,1949
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - other changes
REFERENCE :
   SSCHAH Soap and Sanitary Chemicals.  (New York, NY)  V.14-30, 1938-54.  For
   publisher information, see SCCSC8.  Volume(issue)/page/year: 25,125,1949

                              *** REVIEWS ***
 
   TOXICOLOGY REVIEW
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   32,245,1974

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X8992
       No. of Facilities: 377 (estimated)
       No. of Industries: 2
       No. of Occupations: 1
       No. of Employees: 985 (estimated)
       No. of Female Employees: 985 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***