*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NX5955350
CHEMICAL NAME           : 8-Isoquinolinol,
                          1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-,
                          hydrochloride
BEILSTEIN REFERENCE NO. : 0190342
REFERENCE               : 5-21-05-00514 (Beilstein Handbook Reference)
LAST UPDATED            : 199707
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C12-H17-N-O3.Cl-H
MOLECULAR WEIGHT        : 259.76
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Anhalidin hydrochloride
   * Anhalidine hydrochloride
   * 6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydro-8-isoquinolinol hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 750 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HCACAV Helvetica Chimica Acta.  (Verlag Helvetica Chimica Acta, Postfach,
   CH-4002 Basel, Switzerland) V.1-    1918-  Volume(issue)/page/year:
   49,403,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 310 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HCACAV Helvetica Chimica Acta.  (Verlag Helvetica Chimica Acta, Postfach,
   CH-4002 Basel, Switzerland) V.1-    1918-  Volume(issue)/page/year:
   49,403,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 91 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HCACAV Helvetica Chimica Acta.  (Verlag Helvetica Chimica Acta, Postfach,
   CH-4002 Basel, Switzerland) V.1-    1918-  Volume(issue)/page/year:
   49,403,1966
 
                            *** END OF RECORD ***