*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NX8155810
CHEMICAL NAME           : 4-Isothiazolecarboxy-p-phenetidide,
                          5-benzamido-3-methyl-
CAS REGISTRY NUMBER     : 25392-07-8
BEILSTEIN REFERENCE NO. : 1164396
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H19-N3-O3-S
MOLECULAR WEIGHT        : 381.48
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 5-Benzamido-3-methyl-4-isothiazolecarboxy-p-phenetidide
   * 3-Methyl-5-benzoylaminoisothiazole-4-carboxy-p-ethoxyphenylamide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 517 mg/kg
TOXIC EFFECTS :
   Behavioral - irritability
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB
   1001, 00-068 Warsaw 1, Poland)  V.10-    1962-  Volume(issue)/page/year:
   21,329,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 231 mg/kg
TOXIC EFFECTS :
   Behavioral - irritability
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB
   1001, 00-068 Warsaw 1, Poland)  V.10-    1962-  Volume(issue)/page/year:
   21,329,1973
 
                            *** END OF RECORD ***