*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NX8157203
CHEMICAL NAME           : Isothiazolo(5,4-b)pyridin-3(2H)-one,
                          4,6-dimethyl-2-(2-oxopropyl)-, 1,1-dioxide
CAS REGISTRY NUMBER     : 108361-84-8
LAST UPDATED            : 199209
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C11-H12-N2-O4-S
MOLECULAR WEIGHT        : 268.31
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 4,6-Dimethyl-2-(2-oxopropyl)isothiazolo(5,4-b)pyridin-3(2H)-one  
   1,1-dioxide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 212 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 41,676,1986
 
                            *** END OF RECORD ***