*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : NX8157210
CHEMICAL NAME : Isothiazolo(5,4-d)pyrimidine-4,6(5H,7H)-dione,
5-((p-hydroxybenzylidene)amino)-3-methyl-
CAS REGISTRY NUMBER : 89367-92-0
LAST UPDATED : 198609
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C13-H9-N4-O3-S
MOLECULAR WEIGHT : 301.32
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* 5-((p-Hydroxybenzylidene)amino)-3-methylisothiazolo(5,4-d)pyrimidine-4,6
(5H,7H)-dione
* 5-(4'-Hydroxybenzylidenoimino)-3-methylisothiazolo(5,4-d)pyrimidine-(7H)
-4,6-dione
* IP-10
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 535 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB
1001, 00-068 Warsaw 1, Poland) V.10- 1962- Volume(issue)/page/year:
31,769,1983
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 330 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB
1001, 00-068 Warsaw 1, Poland) V.10- 1962- Volume(issue)/page/year:
31,769,1983
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 275 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB
1001, 00-068 Warsaw 1, Poland) V.10- 1962- Volume(issue)/page/year:
31,769,1983
*** END OF RECORD ***