*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NX4912500
CHEMICAL NAME           : Isoquinoline,
                          1,2,3,4-tetrahydro-1-(2-amino-4-fluorobenzyl)-2-methy
                          l-, dihydrochloride
CAS REGISTRY NUMBER     : 2803-69-2
LAST UPDATED            : 199007
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C17-H19-F-N2.2Cl-H
MOLECULAR WEIGHT        : 343.30
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-(2-Amino-4-fluorobenzyl)-2-methyl-1,2,3,4-tetrahydroisoquinoline  
   dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 6,91,1963
 
                            *** END OF RECORD ***