*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NY2103000
CHEMICAL NAME           : 5-Isoxazoleacetic acid,
                          4,5-dihydro-alpha-amino-3-chloro-, (S-(R*,R*))-
CAS REGISTRY NUMBER     : 42228-92-2
BEILSTEIN REFERENCE NO. : 1074648
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C5-H7-Cl-N2-O3
MOLECULAR WEIGHT        : 178.59
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Acivicine
   * (alpha-S,5S)-alpha-Amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid
   * Antibiotic AT 125
   * AT 125
   * (S-(R*,R*))-4,5-Dihydro-alpha-amino-3-chloro-5-isoxazoleacetic acid
   * NSC-163501
   * U 42126
 
                       *** HEALTH HAZARD DATA ***
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 250 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 223,129,1989
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Bird - chicken Embryo
DOSE/DURATION           : 6 umol/L
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 26,633,1983
 
                            *** END OF RECORD ***