*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : NY2727000
CHEMICAL NAME : 3-Isoxazolecarboxylic acid, 5-methyl-,
2-(alpha-methylphenethyl)hydrazide
CAS REGISTRY NUMBER : 60789-89-1
LAST UPDATED : 199012
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C14-H17-N3-O2
MOLECULAR WEIGHT : 259.34
WISWESSER LINE NOTATION : T5NOJ C1 EVMMY1&1R
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* Hydrazine, 2-(5-methyl-3-isoxazolylcarbonyl)-1-(alpha-methylphenethyl)-
* 3-Isoxazolecarboxylic acid, 5-methyl-,
2-(1-methyl-2-phenylethyl)hydrazide
* 5-Methyl-3-isoxazolecarboxylic acid 2-(alpha-methylphenethyl)hydrazide
* 1-(alpha-Methylphenethyl)-2-(5-methyl-3-isoxazolylcarbonyl)hydrazine
* Ro 5-1226
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 89 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,296,1972
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 94 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,296,1972
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC)
V.1-5, 1959-62. For publisher information, see JMCMAR.
Volume(issue)/page/year: 2,133,1960
*** END OF RECORD ***