*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NY3396800
CHEMICAL NAME           : Isoxazolo(5,4-c)pyridin-3(2H)-one,
                          4,5,6,7-tetrahydro-, hydrate
CAS REGISTRY NUMBER     : 64603-91-4
LAST UPDATED            : 199103
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C6-H8-N2-O2.H2-O
MOLECULAR WEIGHT        : 158.18
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Gaboxadol
   * 4,5,6,7-Tetrahydroisoxazolo(5,4-c)pyridin-3(2H)-one hydrate
   * THIP
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 98 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - ptosis
   Behavioral - somnolence (general depressed activity)
   Skin and Appendages - hair
REFERENCE :
   NEPHBW Neuropharmacology.  (Pergamon Press Ltd., Headington Hill Hall,
   Oxford OX3 OBW, UK) V.9-    1970-  Volume(issue)/page/year: 21,803,1982
 
                            *** END OF RECORD ***