*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NY5980000
CHEMICAL NAME           : Jamaica ginger extract
SUBSTANCE DEFINITION :
   Adulterated with tri-o-cresyl phosphate
REFERENCE :
   JHHBAI Bulletin of the Johns Hopkins Hospital.  (Baltimore, MD)  V.1-119,
   1889-1966.  For publisher information, see JHMJAX.
LAST UPDATED            : 199506
DATA ITEMS CITED        : 2
COMPOUND DESCRIPTOR     : Human
SYNONYMS/TRADE NAMES :
   * Extract of jamaica ginger
   * Fluid-extract of jamaica ginger U.S.P.
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 12 gm/kg/7D
TOXIC EFFECTS :
   Spinal Cord - demyelination
   Spinal Cord - other degenerative changes
   Peripheral Nerve and Sensation - structural change in nerve or sheath
REFERENCE :
   ANPSAI Archives of Neurology and Psychiatry.  (Chicago, IL)  V.1-64,
   1919-50.  For publisher information, see ARNEAS.  Volume(issue)/page/year:
   25,29,1931
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 284 gm/kg/15W
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Behavioral - muscle weakness
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   JHHBAI Bulletin of the Johns Hopkins Hospital.  (Baltimore, MD)  V.1-119,
   1889-1966.  For publisher information, see JHMJAX. Volume(issue)/page/year:
   52,39,1933
 
                            *** END OF RECORD ***