*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OB1085000
CHEMICAL NAME           : Ketone, 2-amino-6-benzimidazolyl phenyl
CAS REGISTRY NUMBER     : 52329-60-9
LAST UPDATED            : 199307
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C14-H11-N3-O
MOLECULAR WEIGHT        : 237.28
WISWESSER LINE NOTATION : T56 BM DNJ CZ GVR
COMPOUND DESCRIPTOR     : Drug
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Benzimidazole, 2-amino-5-benzoyl-
   * G-1029
   * Ketone, 2-amino-5-benzimidazolyl phenyl
   * Methanone, (2-amino-1H-benzimidazol-5-yl)phenyl-
   * R 18986
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 450 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MPPBAB Meditsinskaya Parazitologiya i Parazitarnye Bolezni.  Medical
   Parasitology and Parasitic Diseases.  (V/O Mezhdunarodnaya Kniga, 113095
   Moscow, USSR)  V.1-    1932-  Volume(issue)/page/year: 48(4),29,1979
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 257 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MPPBAB Meditsinskaya Parazitologiya i Parazitarnye Bolezni.  Medical
   Parasitology and Parasitic Diseases.  (V/O Mezhdunarodnaya Kniga, 113095
   Moscow, USSR)  V.1-    1932-  Volume(issue)/page/year: 48(4),29,1979
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 755 mg/kg
SEX/DURATION            : female 8-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 31,505,1976
 
                            *** END OF RECORD ***