*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OB1089000
CHEMICAL NAME           : Ketone, 5-amino-1,3-dimethyl-4-pyrazolyl
                          o-fluorophenyl
CAS REGISTRY NUMBER     : 31272-21-6
BEILSTEIN REFERENCE NO. : 0662779
REFERENCE               : 5-25-15-00191 (Beilstein Handbook Reference)
LAST UPDATED            : 199806
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C12-H12-F-N3-O
MOLECULAR WEIGHT        : 233.27
WISWESSER LINE NOTATION : T5NNJ B1 CZ DVR BF& E1
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * 5-Amino-1,3-dimethyl-4-pyrazolyl o-fluorophenyl ketone
   * (5-Amino-1,3-dimethyl-1H-pyrazol-4-yl)(2-fluorophenyl)methanone
   * Ketone, 5-amino-1,3-dimethylpyrazol-4-yl o-fluorophenyl
   * Methanone, (5-amino-1,3-dimethyl-1H-pyrazol-4-yl)(2-fluorophenyl)-
   * PD 71627
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2366 mg/kg/13W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   AJPAA4 American Journal of Pathology.  (Lippincott/Harper, Journal
   Fulfillment Dept., 2350 Virginia Ave., Hagerstown, MD 21740)  V.1-    1925-
   Volume(issue)/page/year: 124,392,1986
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 10 nmol/plate
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 7,2019,1986
 
                            *** END OF RECORD ***