*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OB1835000
CHEMICAL NAME           : Ketone, 3,5-diiodo-4-hydroxyphenyl
                          2-ethyl-3-benzofuranyl
CAS REGISTRY NUMBER     : 68-90-6
BEILSTEIN REFERENCE NO. : 1257683
REFERENCE               : 5-18-02-00335 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C17-H12-I2-O3
MOLECULAR WEIGHT        : 518.09
WISWESSER LINE NOTATION : T56 BOJ C2 DVR DQ CI EI
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Aethyl-2-(3',5'-dijod-4'-oxybenzoyl)-3 cumaron
   * Algocor
   * Amplivix
   * Benziodaron
   * Benziodarone
   * Benzofuran, 3-(3,5-diiodo-4-hydroxybenzoyl)-2-ethyl-
   * Cardivix
   * Carofam
   * Coronal-crinos
   * 3,5-Diiodo-4-hydroxyphenyl 2-ethyl-3-benzofuranyl ketone
   * Dilafurane
   * Dila-Vasal
   * 2-Ethyl-3-(3',5'-diiodo-4'-hydroxybenzoyl)-cumarone
   * L 2329
   * 2329 Labaz
   * Retrangor
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 450 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YKYUA6 Yakkyoku.  Pharmacy.  (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo,
   Japan)  V.1-    1950-  Volume(issue)/page/year: 24,431,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 130 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YKYUA6 Yakkyoku.  Pharmacy.  (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo,
   Japan)  V.1-    1950-  Volume(issue)/page/year: 24,431,1973
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 10 mg/kg
TOXIC EFFECTS :
   Nutritional and Gross Metabolic - body temperature increase
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 15,1388,1965
 
                            *** END OF RECORD ***