*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : OB3180000 CHEMICAL NAME : Ketone, 4-ethyl-3,5-dimethylpyrrol-2-yl methyl CAS REGISTRY NUMBER : 1500-91-0 BEILSTEIN REFERENCE NO. : 0123442 REFERENCE : 5-21-07-00264 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C10-H15-N-O MOLECULAR WEIGHT : 165.26 WISWESSER LINE NOTATION : T5MJ BV1 C1 D2 E1 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * 2-Acetyl-3,5-dimethyl-4-ethyl-pyrrole * 4-Ethyl-3,5-dimethylpyrrol-2-yl methyl ketone *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 400 mg/kg TOXIC EFFECTS : Behavioral - anticonvulsant Behavioral - sleep Behavioral - somnolence (general depressed activity) REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 11,1251,1968 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 767 mg/kg TOXIC EFFECTS : Brain and Coverings - recordings from specific areas of CNS Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay) REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 11,1251,1968 *** END OF RECORD ***