*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : NY6573000 CHEMICAL NAME : Jatropha curcus, fruit or seeds SUBSTANCE DEFINITION : A tree belonging to the family Euphorbiaceae REFERENCE : PLMEAA Planta Medica. (Georg Thieme Verlag, Postfach 732, D-7000 Stuttgart 1, Fed. Rep. Ger.) V.1- 1953- Volume(issue)/page/year: 11,98,1963 LAST UPDATED : 199506 DATA ITEMS CITED : 2 COMPOUND DESCRIPTOR : Reproductive Effector Natural Product *** HEALTH HAZARD DATA *** ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - domestic DOSE/DURATION : 5250 mg/kg/3W-I TOXIC EFFECTS : Liver - fatty liver degeneration Nutritional and Gross Metabolic - dehydration Related to Chronic Data - death REFERENCE : TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 4,347,1975 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE : 41250 mg/kg SEX/DURATION : female 25 day(s) pre-mating TOXIC EFFECTS : Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated) REFERENCE : PLMEAA Planta Medica. (Georg Thieme Verlag, Postfach 732, D-7000 Stuttgart 1, Fed. Rep. Ger.) V.1- 1953- Volume(issue)/page/year: 11,98,1963 *** END OF RECORD ***