*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NY8186000
CHEMICAL NAME           : Jectofer
CAS REGISTRY NUMBER     : 62765-90-6
LAST UPDATED            : 199806
DATA ITEMS CITED        : 3
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Iron-sorbitol
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 25 mg(Fe)/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NNAPBA Naunyn-Schmiedebergs Archiv fuer Pharmakologie.  (Berlin, Ger.)
   V.264-271, 1969-71.  For publisher information, see NSAPCC.
   Volume(issue)/page/year: 270(Suppl),R50,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 44 mg(Fe)/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 27,114,1966
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 200 mg(Fe)/kg
SEX/DURATION            : female 12-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   SJHSBD Scandinavian Journal of Haematology, Supplementum.  (Munksgaard
   International Pub., POB 2148, DK-1016 Copenhagen K, Denmark)  No.1- 1967- 
   Volume(issue)/page/year: 32,69,1977
 
                            *** END OF RECORD ***