*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : NY9000000
CHEMICAL NAME : Jervine,
11-deoxo-12-beta,13-alpha-dihydro-11-alpha-hydroxy-
CAS REGISTRY NUMBER : 73825-59-9
LAST UPDATED : 198909
DATA ITEMS CITED : 2
MOLECULAR FORMULA : C26-H40-N-O3
MOLECULAR WEIGHT : 414.67
WISWESSER LINE NOTATION : L D6 B566 FX LUTJ A1 CQ OQ F-& CT56 BOX FMTJ D1 H1
COMPOUND DESCRIPTOR : Reproductive Effector
SYNONYMS/TRADE NAMES :
* 11-Deoxo-12-beta,13-alpha-dihydro-11-alpha-hydroxyjervine
* 12-beta,13-alpha-Dihydrojervine-11-alpha-ol
*** HEALTH HAZARD DATA ***
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - hamster
DOSE : 113 mg/kg
SEX/DURATION : female 7 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
resorbed implants per total number of implants)
REFERENCE :
JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC
20037) V.1- 1953- Volume(issue)/page/year: 26,561,1978
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - hamster
DOSE : 150 mg/kg
SEX/DURATION : female 7 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - Central Nervous System
Reproductive - Specific Developmental Abnormalities - eye/ear
Reproductive - Specific Developmental Abnormalities - craniofacial
(including nose and tongue)
REFERENCE :
JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC
20037) V.1- 1953- Volume(issue)/page/year: 26,561,1978
*** END OF RECORD ***