*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OB6336500
CHEMICAL NAME           : Ketone, 1-(2-morpholinoethyl)-4-phenyl-4-piperidyl
                          phenyl, dihydrochloride
CAS REGISTRY NUMBER     : 25224-24-2
LAST UPDATED            : 198809
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C24-N30-N2-O2.2Cl-H
MOLECULAR WEIGHT        : 841.48
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-(2-Morpholinoethyl)-4-phenyl-4-piperidyl phenyl ketone dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 161 mg/kg
TOXIC EFFECTS :
   Behavioral - analgesia
REFERENCE :
   APPFAR Acta Poloniae Pharmaceutica (English Translation).  Translation of
   APPHAX.  (Warsaw, Poland) V.20-29, 1963-72.  Discontinued.
   Volume(issue)/page/year: 27,392,1970
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 435 mg/kg
TOXIC EFFECTS :
   Behavioral - analgesia
REFERENCE :
   APPFAR Acta Poloniae Pharmaceutica (English Translation).  Translation of
   APPHAX.  (Warsaw, Poland) V.20-29, 1963-72.  Discontinued.
   Volume(issue)/page/year: 27,392,1970
 
                            *** END OF RECORD ***