*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OD5400000
CHEMICAL NAME           : Lactic acid, compd. with
                          1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(3-methyl-2-but
                          enyl)-2,6- methano-3-benzazocin-8-ol (1:1)
CAS REGISTRY NUMBER     : 17146-95-1
LAST UPDATED            : 199504
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C19-H27-N-O.C3-H6-O3
MOLECULAR WEIGHT        : 375.56
WISWESSER LINE NOTATION : T C666 A KN&TTJ A1 B1 EQ K2UY1&1 &QY1&VQ
COMPOUND DESCRIPTOR     : Human
SYNONYMS/TRADE NAMES :
   * Pentazocine lactate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 2 mg/kg
TOXIC EFFECTS :
   Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
   ARDEAC Archives of Dermatology.  (AMA, 535 N. Dearborn St., Chicago, IL
   60610)  V.82-    1960-  Volume(issue)/page/year: 123,297,1987
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 16 mg/kg/3W-I
TOXIC EFFECTS :
   Musculoskeletal - other changes
REFERENCE :
   JRHUA9 Journal of Rheumatology.  (920 Yonge St., Suite 608, Toronto, Ont.,
   Canada)  V.1-    1974-  Volume(issue)/page/year: 13,210,1986
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 103 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 23,882,1971

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X5606
       No. of Facilities: 10 (estimated)
       No. of Industries: 1
       No. of Occupations: 1
       No. of Employees: 340 (estimated)
       No. of Female Employees: 180 (estimated)

 
                            *** END OF RECORD ***