*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : OD5500000 CHEMICAL NAME : Lactic acid, 3-(p-hydroxyphenyl)- CAS REGISTRY NUMBER : 306-23-0 LAST UPDATED : 199803 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C9-H10-O4 MOLECULAR WEIGHT : 182.19 WISWESSER LINE NOTATION : QVY1&OR DQ COMPOUND DESCRIPTOR : Tumorigen Reproductive Effector SYNONYMS/TRADE NAMES : * Benzenepropanoic acid, alpha,4-dihyroxy- * HPLA * beta-(p-Hydroxyphenyl)lactic acid * beta-(4-Hydroxyphenyl)lactic acid * p-Hydroxyphenyllactic acid * 3-(4-Hydroxyphenyl)lactic acid *** HEALTH HAZARD DATA *** ** TUMORIGENIC DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 800 mg/kg female 15-21 day(s) after conception TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Reproductive - Tumorigenic effects - transplacental tumorigenesis Lungs, Thorax, or Respiration - tumors REFERENCE : BEXBAN Bulletin of Experimental Biology and Medicine (English Translation). Translation of BEBMAE. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.41- 1956- Volume(issue)/page/year: 87,46,1979 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 800 mg/kg female 15-21 day(s) after conception TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Reproductive - Tumorigenic effects - transplacental tumorigenesis Blood - tumors REFERENCE : BEXBAN Bulletin of Experimental Biology and Medicine (English Translation). Translation of BEBMAE. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.41- 1956- Volume(issue)/page/year: 87,46,1979 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1600 mg/kg/8W-I TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors REFERENCE : VOONAW Voprosy Onkologii. Problems of Oncology. For English translation, see PONCAU. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-10, 1928-37; V.1- 1955- Volume(issue)/page/year: 22(6),47,1976 TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2800 mg/kg/10W-I TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors Blood - leukemia REFERENCE : GETRE8 Gematologiya i Transfuziologiya. Hematology and Transfusion Science. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.28- 1983- Volume(issue)/page/year: 28(2),50,1983 *** END OF RECORD ***