*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OD5735000
CHEMICAL NAME           : Lactic acid, compd. with
                          alpha-5-norbornen-2-yl-alpha-phenyl-1-piperidinepropa
                          nol (1:1)
CAS REGISTRY NUMBER     : 7085-45-2
LAST UPDATED            : 198710
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C21-H29-N-O.C3-H6-O3
MOLECULAR WEIGHT        : 401.60
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Akineton lactate
   * Biperiden lactate
   * alpha-5-Norbornen-2-yl-alpha-phenyl-1-piperidinepropanol compd. with  
   lactic acid (1:1)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 161 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 1,74,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 335 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 1,74,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 61 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 1,74,1967
 
                            *** END OF RECORD ***