*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OG1225000
CHEMICAL NAME           : Lead(II) fluoride
CAS REGISTRY NUMBER     : 7783-46-2
LAST UPDATED            : 199712
DATA ITEMS CITED        : 49
MOLECULAR FORMULA       : F2-Pb
MOLECULAR WEIGHT        : 245.19
WISWESSER LINE NOTATION :  PB  F2
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Lead difluoride
   * Plomb fluorure
   * Plumbous fluoride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3031 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle weakness
   Lungs, Thorax, or Respiration - respiratory stimulation
   Skin and Appendages - hair
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 35(8),43,1991
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3015 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle weakness
   Lungs, Thorax, or Respiration - respiratory stimulation
   Skin and Appendages - hair
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 35(8),43,1991
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Amphibian - frog
DOSE/DURATION           : 2800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses
   Filiales.  (SPPIF, B.P.22, F-41353 Vineuil, France)  V.1-    1849-
   Volume(issue)/page/year: 124,133,1937
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 5 mg/m3/4H
SEX/DURATION            : male 17 week(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
   sperm morphology, motility, and count)
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 57(3),28,1992
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 50 mg/m3/4H
SEX/DURATION            : male 17 week(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 57(3),28,1992

                              *** REVIEWS ***
 
   ACGIH TLV-TWA 0.05 mg(Pb)/m3; animal carcinogen
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   TOXICOLOGY REVIEW
   AMSSAQ Acta Medica Scandinavica, Supplement.  (Almqvist & Wiksell, POB
   45150, S-10430 Stockholm, Sweden)  No.1-730, 1921-88.
   Volume(issue)/page/year: 400,5,1963

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   OSHA PEL (Gen Indu):8H TWA 2.5 mg(F)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1910.1000,1994

   OSHA PEL (Construc):8H TWA 2.5 mg(F)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1926.55,1994

   OSHA PEL (Shipyard):8H TWA 2.5 mg(F)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1915.1000,1993

   OSHA PEL (Fed Cont):8H TWA 2.5 mg(F)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   41,50-204.50,1994

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-ARAB Republic of Egypt:TWA 0.05 mg(Pb)/m3 JAN 1993
   
   OEL-AUSTRALIA:TWA 0.15 mg(Pb)/m3 JAN 1993
   
   OEL-AUSTRALIA:TWA 2.5 mg(F)/m3 JAN 1993
   
   OEL-AUSTRIA:TWA 0.1 mg(Pb)/m3 JAN 1993
   
   OEL-BELGIUM:TWA 0.15 mg(Pb)/m3 JAN 1993
   
   OEL-BELGIUM:TWA 2.5 mg(F)/m3 JAN 1993
   
   OEL-DENMARK:TWA 0.1 mg(Pb)/m3 JAN 1993
   
   OEL-DENMARK:TWA 2.5 mg(F)/m3 JAN 1993
   
   OEL-FINLAND:TWA 0.1 mg(Pb)/m3 JAN 1993
   
   OEL-FINLAND:TWA 2.5 mg(F)/m3 JAN 1993
   
   OEL-FRANCE:TWA 0.15 mg(Pb)/m3 JAN 1993
   
   OEL-FRANCE:TWA 2.5 mg(F)/m3 JAN 1993
   
   OEL-GERMANY:TWA 0.1 mg(Pb)/m3 JAN 1993
   
   OEL-GERMANY:TWA 2.5 mg(F)/m3 JAN 1993
   
   OEL-HUNGARY:STEL 0.04 mg(Pb)/m3;Carcinogen JAN 1993
   
   OEL-HUNGARY:TWA 1 mg(F)/m3;STEL 2 mg(F)/m3 JAN 1993
   
   OEL-THE NETHERLANDS:TWA 2.5 mg(F)/m3 JAN 1993
   
   OEL-THE PHILIPPINES:TWA 0.15 mg(Pb)/m3 JAN 1993
   
   OEL-THE PHILIPPINES:TWA 2.5 mg(F)/m3 JAN 1993
   
   OEL-POLAND:TWA 1 mg(F)/m3 JAN 1993
   
   OEL-RUSSIA:STEL 0.005 ppm (0.01 mg(Pb)/m3) JAN 1993
   
   OEL-SWEDEN:TWA 0.05 mg(Pb)/m3 (resp. dust) JAN 1993
   
   OEL-SWEDEN:TWA 0.1 mg(Pb)/m3 (total dust) JAN 1993
   
   OEL-SWEDEN:TWA 2 mg(F)/m3 JAN 1993
   
   OEL-SWITZERLAND:TWA 0.1 mg(Pb)/m3 JAN 1993
   
   OEL-SWITZERLAND:TWA 1.8 ppm (1.5 mg(F)/m3);STEL 9.0 ppm JAN 1993
   
   OEL-THAILAND:TWA 0.2 mg(Pb)/m3 JAN 1993
   
   OEL-THAILAND:TWA 2.5 mg(F)/m3 JAN 1993
   
   OEL-TURKEY:TWA 0.2 mg(Pb)/m3 JAN 1993
   
   OEL-TURKEY:TWA 2.5 mg(F)/m3 JAN 1993
   
   OEL-UNITED KINGDOM:TWA 0.15 mg(Pb)/m3 JAN 1993
   
   OEL-UNITED KINGDOM:TWA 2.5 mg(F)/m3 JAN 1993
   
   OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
   
   OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
   NIOSH REL TO LEAD, INORGANIC-air:10H TWA <0.1 mg(Pb)/m3
REFERENCE :
   NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
   Health, Education, and Welfare, Reports and Memoranda.
   Volume(issue)/page/year: DHHS #92-100,1992

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 83015
       No. of Facilities: 188 (estimated)
       No. of Industries: 6
       No. of Occupations: 12
       No. of Employees: 3241 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 83015
       No. of Facilities: 25 (estimated)
       No. of Industries: 5
       No. of Occupations: 8
       No. of Employees: 2438 (estimated)
       No. of Female Employees: 601 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***