*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : OH2921000
CHEMICAL NAME : Leucine, N-carboxy-, N-benzyl ester, L-
CAS REGISTRY NUMBER : 2018-66-8
BEILSTEIN REFERENCE NO. : 1253861
REFERENCE : 3-06-00-01503 (Beilstein Handbook Reference)
LAST UPDATED : 199612
DATA ITEMS CITED : 2
MOLECULAR FORMULA : C14-H19-N-O4
MOLECULAR WEIGHT : 265.34
COMPOUND DESCRIPTOR : Reproductive Effector
SYNONYMS/TRADE NAMES :
* Benzyloxycarbonylleucine
* Benzyloxycarbonyl-L-leucine
* N-Benzyloxycarbonylleucine
* Carbobenzoxyleucine
* Carbobenzoxy-L-leucine
* N-Carbobenzoxy-L-leucine
* Carbobenzyloxy-L-leucine
* L-N-Carboxyleucine N-benzyl ester
* L-Leucine, N-((phenylmethoxy)carbonyl)-
* N-((Phenylmethoxy)carbonyl)-L-leucine
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravaginal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : >1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc.,
2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961-
Volume(issue)/page/year: 68,696,1979
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intravaginal
SPECIES OBSERVED : Rodent - mouse
DOSE : 280 mg/kg
SEX/DURATION : female 28 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - female fertility index (e.g. # females pregnant
per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc.,
2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961-
Volume(issue)/page/year: 68,696,1979
*** END OF RECORD ***