*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OH4725813
CHEMICAL NAME           : Leucomycin V, 3-acetate 4(sup B)-(3-methylbutanoate),
                          (R-(R*,R*))-2,3-dihydroxybutanedioate (salt)
CAS REGISTRY NUMBER     : 52454-74-7
LAST UPDATED            : 198903
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C42-H69-N-O15.C4-H6-O6
MOLECULAR WEIGHT        : 978.22
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Josamycin tartrate
   * Leucomycin A3 tartrate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JAJAAA Journal of Antibiotics, Series A.  (Tokyo, Japan)  V.6-20, 1953-67.
   For publisher information, see JANTAJ.  Volume(issue)/page/year: 20,181,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 304 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NKRZAZ Chemotherapy (Tokyo).  (Nippon Kagaku Ryoho Gakkai, 2-20-8 Kamiosaki,
   Shinagawa-Ku, Tokyo 141, Japan)  V.1-    1953- Volume(issue)/page/year:
   17,576,1969
 
                            *** END OF RECORD ***