*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OJ9457420
CHEMICAL NAME           : Lonomycin A, 11-O-demethyl-23,27-didemethoxy-,
                          monosodium salt
CAS REGISTRY NUMBER     : 62696-99-5
LAST UPDATED            : 199103
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C41-H69-O12.Na
MOLECULAR WEIGHT        : 777.09
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Antibiotic S 11743A sodium salt
   * 11-O-Demethyl-23,27-didemethoxylonomycin A sodium
   * Mutalomycin sodium
   * S 11743A sodium salt
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 8 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 42,897,1989
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 42,897,1989
 
                            *** END OF RECORD ***