*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OK6390000
CHEMICAL NAME           : Luteinizing hormone-releasing hormone, (AC-delta(sup
                          3)-pro(sup 1)-p-F-D-phe(sup 2)- D-trp(sup 3,6))-
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
COMPOUND DESCRIPTOR     : Reproductive Effector
                          Hormone
SYNONYMS/TRADE NAMES :
   * (AC-delta(sup 3)-Pro(sup 1)-p-F-D-phe(sup 2)-D-trp(sup 3,6))-Gnrh
   * (AC-delta(sup 3)-Pro(sup 1)-p-F-D-phe(sup 2)-D-trp(sup 3,6))-gonadotropin 
    releasing hormone
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 300 ug/kg
SEX/DURATION            : male 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - other effects on male
REFERENCE :
   ENDOAO Endocrinology (Baltimore).  (Williams & Wilkins Co., 428 E. Preston
   St., Baltimore, MD 21203) V.1-    1917-  Volume(issue)/page/year:
   108,1998,1981
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 3 mg/kg
SEX/DURATION            : female 5-7 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - other measures of fertility
REFERENCE :
   BIREBV Biology of Reproduction.  (Soc. for the Study of Reproduction, 309 W.
   Clark St., Champaign, IL 61820)  V.1-    1969-  Volume(issue)/page/year:
   24,1061,1981
 
                            *** END OF RECORD ***