*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OK6410000
CHEMICAL NAME           : Luteinizing hormone-releasing hormone, (D-ala(sup
                          6)-des-gly(sup 10))-, ethylamide
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
COMPOUND DESCRIPTOR     : Reproductive Effector
                          Hormone
SYNONYMS/TRADE NAMES :
   * (D-Ala(sup 6)-des-gly(sup 10))-LHRH ethylamide
   * (D-Ala(sup 6)-des-gly(sup 10))-luteinizing hormone-releasing hormone  
   ethylamide
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 875 ug/kg
SEX/DURATION            : female 1-7 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
REFERENCE :
   BBRCA9 Biochemical and Biophysical Research Communications.  (Academic
   Press, Inc., 1 E. First St., Duluth, MN 55802)  V.1-    1959-
   Volume(issue)/page/year: 72,1003,1976
 
                            *** END OF RECORD ***