*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OK6509000
CHEMICAL NAME           : Luteinizing hormone-releasing hormone,
                          2-L-histidine-6-L-glycine-
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
COMPOUND DESCRIPTOR     : Reproductive Effector
                          Hormone
SYNONYMS/TRADE NAMES :
   * (L-His(sup 2)-L-gly(sup 6))-LHRH
   * (L-His(sup 2)-L-gly(sup 6))-luteinizing hormone-releasing hormone
   * Luteinizing hormone-releasing hormone, (L-his(sup 2)-L-gly(sup 6))-
   * WY 16,558
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 7 mg/kg
SEX/DURATION            : female 1-7 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - other measures of fertility
REFERENCE :
   IJGOAL International Journal of Gynaecology & Obstetrics.  (Elsevier
   Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland)  V.7-    1969-
   Volume(issue)/page/year: 16,359,1979
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 600 ug/kg
SEX/DURATION            : female 7-12 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   IJGOAL International Journal of Gynaecology & Obstetrics.  (Elsevier
   Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland)  V.7-    1969-
   Volume(issue)/page/year: 16,359,1979
 
                            *** END OF RECORD ***