*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OK6702000
CHEMICAL NAME           : Luteinizing hormone-releasing hormone, (D-ser-(Bu(sup
                          t))(sup 6)-des-gly)-, ethylamide
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
COMPOUND DESCRIPTOR     : Reproductive Effector
                          Hormone
SYNONYMS/TRADE NAMES :
   * (D-Ser-(Bu(sup t))(sup 6)-des-gly)-LHRH ethylamide
   * (D-Ser-(Bu(sup t))(sup 6)-des-gly)-luteinizing hormone-releasing hormone  
   ethylamide
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Primate - monkey
DOSE                    : 365 ug/kg
SEX/DURATION            : female 52 week(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Maternal Effects - ovaries, fallopian tubes
   Reproductive - Maternal Effects - uterus, cervix, vagina
   Reproductive - Fertility - other measures of fertility
REFERENCE :
   CCPTAY Contraception.  (Geron-X, Inc., POB 1108, Los Altos, CA 94022)  V.1-
   1970-  Volume(issue)/page/year: 24,647,1981
 
                            *** END OF RECORD ***