*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OL5615000
CHEMICAL NAME           : Lysine, N(sup
                          6)-((4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro
                          -3,6,10,12,12a-
                          pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxa
                          mido)methyl)-, (+)-
CAS REGISTRY NUMBER     : 992-21-2
LAST UPDATED            : 199201
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C29-H38-N4-O10
MOLECULAR WEIGHT        : 602.71
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * N(sup 2)-(((+)-5-Amino-5-carboxypentylamino)methyl)tetracycline
   * Armyl
   * Lymecycline
   * N-Lysinomethyltetracycline
   * Mucomycin
   * Tetraciclina-L-metilenlisina
   * Tetracycline, lysinomethyl-
   * Tetracycline-L-methylene lysine
   * Tetralisal
   * Tetralysal
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 181 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   RPOBAR Research Progress in Organic-Biological and Medicinal Chemistry. (New
   York, NY)  V.1-3, 1964-72.  Discontinued.  Volume(issue)/page/year:
   2,333,1970
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 253 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BMJOAE British Medical Journal.  (British Medical Assoc., BMA House,
   Tavistock Sq., London WC1H 9JR, UK)  V.1-    1857- Volume(issue)/page/year:
   2,106,1964
 
                            *** END OF RECORD ***