*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : OM0848200
CHEMICAL NAME : Madumycin I, 15-deoxo-15-hydroxy-, (15S)-
CAS REGISTRY NUMBER : 58717-24-1
LAST UPDATED : 199206
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C26-H37-N3-O7
MOLECULAR WEIGHT : 503.66
WISWESSER LINE NOTATION : T5-23- A AN CO FVM IVO OVM MU RU TU&TJ H1 KY1&1 L1 T1
VQ A&Q
COMPOUND DESCRIPTOR : Drug
Natural Product
SYNONYMS/TRADE NAMES :
* A-2315
* A-2315A
* Antibiotic A 2315
* Antibiotic A 2315A
* Madumicin II
* Madumycin II
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD - Lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : >500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8
Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968-
Volume(issue)/page/year: 29,76-32,1976
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca
Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 4(2),199,1980
TYPE OF TEST : LD - Lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : >500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8
Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968-
Volume(issue)/page/year: 29,76-32,1976
*** END OF RECORD ***