*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OO0625000
CHEMICAL NAME           : Malonic acid, butyl-, mono(1,2-diphenylhydrazide),
                          calcium salt, hemihydrate
CAS REGISTRY NUMBER     : 69365-73-7
LAST UPDATED            : 199512
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C38-H42-N4-O6.Ca.1/2H2-O
MOLECULAR WEIGHT        : 699.93
WISWESSER LINE NOTATION : OVY4&VNR&MR 2 &-CA- &QH &17/1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Bumadizon calcium salt hemihydrate
   * Butylmalonic acid mono(1,2-diphenylhydrazide) calcium salt hemihydrate
   * Butyl-malonsaeure-mono-(1,2-diphenyl-hydrazid)-calcium-semihydrat
   * Butylpropanedioic acid mono(1,2-diphenylhydrazide) calcium salt  
   hemihydrate
   * alpha-Carboxycaproyl-N,N'-diphenylhydrazine calcium salt hemihydrate
   * N-(2-Carboxycaproyl)hydrazobenzene calcium salt hemihydrate
   * Rheumatol
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 23,1215,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 263 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 23,1215,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 23,1215,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 258 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 23,1215,1973
 
                            *** END OF RECORD ***