*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OO9310000
CHEMICAL NAME           : Manganese, bis(L-histidinato)-, tetrahydrate
CAS REGISTRY NUMBER     : 63270-67-7
LAST UPDATED            : 199701
DATA ITEMS CITED        : 19
MOLECULAR FORMULA       : C12-H16-Mn-N6-O4.4H2-O
MOLECULAR WEIGHT        : 435.36
COMPOUND DESCRIPTOR     : Drug
                          Organometallic
SYNONYMS/TRADE NAMES :
   * Bis(L-histidinato)manganese tetrahydrate
   * Manganese, bis(L-histidinato-N,O)-, tetrahydrate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 160 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   FRMBAZ Farmacia (Bucharest).  (Rompresfilatelia, POB 12-201, Bucharest,
   Romania)  V.1-    1953-  Volume(issue)/page/year: 29,215,1981

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   MSHA STANDARD-air:CL 5 mg(Mn)/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   3,149,1971

   OSHA PEL (Gen Indu):CL 5 mg(Mn)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1910.1000,1994

   OSHA PEL (Construc):CL 5 mg(Mn)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1926.55,1994

   OSHA PEL (Shipyard):CL 5 mg(Mn)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1915.1000,1993

   OSHA PEL (Fed Cont):CL 5 mg(Mn)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   41,50-204.50,1994

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-AUSTRALIA:TWA 5 mg(Mn)/m3 JAN 1993
   
   OEL-BELGIUM:TWA 5 mg(Mn)/m3 JAN 1993
   
   OEL-DENMARK:TWA 2.5 mg(Mn)/m3 JAN 1993
   
   OEL-FINLAND:TWA 2.5 mg(Mn)/m3 JAN 1993
   
   OEL-HUNGARY:TWA 0.3 mg(Mn)/m3;STEL 0.6 mg(Mn)/m3 JAN 1993
   
   OEL-JAPAN:TWA 0.3 mg(Mn)/m3 JAN 1993
   
   OEL-THE NETHERLANDS:TWA 1 mg(Mn)/m3 JAN 1993
   
   OEL-POLAND:TWA 0.3 mg(Mn)/m3 JAN 1993
   
   OEL-SWEDEN:TWA 1 mg(Mn)/m3;STEL 2.5 mg(Mn)/m3  (resp. dust) JAN 1993
   
   OEL-SWEDEN:TWA 2.5 mg(Mn)/m3;STEL 5 mg(Mn)/m3  (total dust) JAN 1993
   
   OEL-UNITED KINGDOM:TWA 5 mg(Mn)/m3 JAN 1993
   
   OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
   
   OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

 
                            *** END OF RECORD ***