*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OP2880000
CHEMICAL NAME           : D-Mannitol,
                          1,6-dideoxy-1,6-bis((2-hydroxyethyl)amino)-,
                          1,6-dimethanesulfonate (ester), dihydrochloride
CAS REGISTRY NUMBER     : 1446-35-1
LAST UPDATED            : 198803
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C12-H28-N2-O10-S2.Cl-H
MOLECULAR WEIGHT        : 461.00
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * R 49
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 60 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NEOLA4 Neoplasma.  (Karger-Libri, P.O. Box, CH-4009 Basel, Switzerland) V.4-
      1957-  Volume(issue)/page/year: 11,529,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 40 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NEOLA4 Neoplasma.  (Karger-Libri, P.O. Box, CH-4009 Basel, Switzerland) V.4-
      1957-  Volume(issue)/page/year: 11,529,1964
 
                            *** END OF RECORD ***