*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OP4099000
CHEMICAL NAME           : beta-D-Mannopyranoside,
                          O-4-C-(1-methoxyethyl)-2,3-O-methylenepentopyranosyli
                          dene-(1-3-4)-2- O-methyl-alpha-L-lyxopyranosyl
                          O-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitro-alpha-
                          L-
                          arabino-hexopyranosyl-(1-3)-O-2,6-dideoxy-4-O-(3,5-di
                          chloro-4-hydroxy-2-me thoxy-6-
                          methylbenzoyl)-beta-D-arabino-hexopyranosyl-(1-4)-0-2
                          ,6-dideoxy-D-ribo-hex opyranosylidene-
                          (1-3-4)-O-6-deoxy-3-C-methyl-beta-D-mannopyranosyl-(1
                          -3)-O-6-deoxy-4-O-met hyl-beta-D-
                          galactopyranosyl-(1-4)-2,6-di-O-methyl-
CAS REGISTRY NUMBER     : 53296-30-3
OTHER CAS REGISTRY NOS. : 50925-95-6
LAST UPDATED            : 198910
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C66-H99-Cl2-N-O36
MOLECULAR WEIGHT        : 1553.56
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Everninomycin-B
   * R-451-B
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 880 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 1,354,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1700 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 1,354,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 875 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 1,354,1980
 
                            *** END OF RECORD ***